Shares of Izotropic Rise1 as Prototype of New 3D Breast Imaging Device Is Unveiled

Editorial | Feb 23, 2023 | Tech 

Little-known Izotropic Corporation (OTCQB:IZOZF | CSE:IZOOTCQB:IZOZF | CSE:IZO) could be the investment opportunity of 2023.

Savvy investors know a quick way to make money is by investing early in a new medical technology with the potential to impact the lives of millions.

For example, early investors in Transmedics Group (TMDX), which makes devices to aid organ transplants, saw their shares skyrocket in 2022 – despite the overall sell-off in the stock market.

The shares rose in price from $142 a share in January 2022 to over $613 a share by the end of the year – a gain of 328%4 in just 12 months.

Now something similar could be happening with a small, little-known medical device company called Izotropic Corporation (OTCQB:IZOZF | CSE:IZOOTCQB:IZOZF | CSE:IZO).

Fully Engineered Device Now Revealed

After years of testing and development, the company has unveiled its long-awaited, pre-commercial prototype of a revolutionary new 3D breast imaging technology, dubbed IzoView.

This completed prototype comes after four successive, fully-functioning breast CT prototypes were developed at UC Davis Medical Center as an academic pursuit.  Commercialization efforts began when Izotropic was granted the exclusive global licensing rights to the technology from The Regents of The University of California.

The device could be a game-changer for women’s health — potentially improving and even saving the lives of thousands of women every year.

The breakthrough breast imaging platform could allow radiologists to view high-resolution 3D images comparable to MRI as part of the initial, low-cost, low-radiation dose routine breast cancer imaging in the future – as many as 40 million per year – and not have to order and then wait for expensive follow-up tests.

The “buzz” surrounding this new technology is real.  The new device will be featured on an upcoming segment of the national TV show “Advancements with Ted Danson” via Amazon Prime Video and Bloomberg TV.5

Shares Jump 112% in Last 6 Months in 2022

Based on reports of early design proposals alone, shares of  Izotropic Corporation (OTCQB:IZOZF | CSE:IZOOTCQB:IZOZF | CSE:IZO) soared 112 percent6 in the second half of 2022.

The reason for the interest is obvious. According to the American Cancer Society, approximately 1 in 8 women (13%) will be diagnosed with invasive breast cancer at some point in their lifetime.

In raw numbers, that means every year in the United States 297,0007 women get the bad news – and 43,0008 die from the disease.

Plus, IzoView revolutionizes how women have diagnostic procedures performed.

A New, More Comfortable, More Private Method for Breast Imaging

A traditional diagnostic x-ray mammogram can require up to 12 individual “views,” with each view taking up to 20 seconds of painful, sometimes agonizing compression to complete. 

Between each view, a technician has to handle the patient’s breast as it is repositioned in the compression plates.  As a result, an x-ray mammogram can take between 20 and 45 minutes to complete.

What’s more, the images produced are often not ideal. Anatomical structures can be distorted, and there is no differentiation between macro-and micro-calcifications in the breast tissue – crucial for identifying potential tumors.

IzoView is radically different. Instead of women standing in front of an old-fashioned x-ray machine that requires vice-like breast compression between metal plates, the Izotropic device lets women lie on a comfortable tabletop and place their own breast in an opening in the table. 

Beneath the bed-like table, an advanced computed tomography (CT) camera moves around the breast in a 360-degree circle, taking approximately 500 images in just 10 seconds. 

Proprietary AI computer software then takes these 500 raw image slices of the non-compressed breast and reconstructs the slices into high-resolution 3D images of the entire breast.

The pre-commercialized prototypes created at UC Davis have been used in extensive academic clinical trials with more than 600 patients. UC Davis is currently in the data analysis stage of a clinical trial comparing breast CT to MRI, with the results to be released soon.

The Advantages of High-Resolution 3D Imaging Over Traditional Mammograms

The greater comfort and privacy are of paramount importance, but they are merely two of the many benefits of IzoView CT imaging for breast diagnostics. 

First, Izotropic Corporation’s (OTCQB:IZOZF | CSE:IZOOTCQB:IZOZF | CSE:IZO) breakthrough 3D imaging system eliminates compression altogether.

Natural breast orientation is preserved with the patient placing her own breast in the imaging cup, so there is no embarrassing handling by a technician.  This also ensures that there is excellent visualization with contrast.

Further, the imaging procedure is over in a flash.  The system takes 500 high-resolution images in approximately 10 seconds with about the same level of radiation from just two traditional mammogram views. 

What’s more, Izotropic is developing new image reconstruction software utilizing the latest machine learning algorithms to deliver both high resolution and low noise images at low radiation dose levels.

Aside from improved detection capabilities, IzoView is a potential solution for more precise margin analysis (viewing edges of a tumor), better “lesion characterization” (the detailed description of an abnormality), and higher spatial resolution, allowing radiologists to better differentiate internal breast structures.

Women and Doctors Eager for the “Next Stage” in Breast Health

As a result, the “buzz” is substantial around this potentially breakthrough technology in women’s health – and it’s not just investors that are so excited about the IzoView 3D imaging platform.

Patients are already asking when the technology will be available and for a good reason! 

The IzoView 3D imaging platform is…

  • A solution for Patients: Patients enjoy a pain-free, comfortable, and more private procedure that is over in seconds rather than in 20 to 45 minutes.
  • A solution for Doctors: Doctors benefit because the 3D visualization and contrast expand use cases and can aid diagnosis
  • A solution for Hospitals & Clinics: The 3D imaging system can improve patient throughput and attract more customers
  • A solution for Insurers: Could lower costs by lowering the number of false positives that lead to unnecessary (and costly) biopsies

Half of Women Will Likely Get a Devastating False Breast Cancer Diagnosis

False positives are common in traditional breast imaging:  False positives are when old-fashioned mammograms reveal abnormalities in the breast tissue that later tests and biopsies reveal are actually benign and not cancerous tumors.

About 50 percent of women who get annual mammograms over a ten-year period will have a false-positive finding at least once.

The problem is, these false positives cause tremendous stress and worry for thousands of women, not to mention unnecessary biopsy procedures – and the follow-up imaging exams and biopsies can cost tens of thousands of dollars per patient.

The Market for Breast Imaging to Soar to $5.4 Billion by 2025

Thus, the market for Izotropic Corporation’s (OTCQB:IZOZF | CSE:IZOOTCQB:IZOZF | CSE:IZO) new breast imaging platform is potentially enormous.  It’s estimated that the market for breast imaging technology will grow from $3.7 billion in 2020 to $5.4 billion by 2025.9

What’s more, 40 million women receive a mammogram each year in the United States.

Of these, about 10 percent – or 4 million — are called back for expensive follow-up tests, such as diagnostic mammograms, tomosynthesis, ultrasound, MRI, and biopsies.10

An advanced breast imaging technology like the one Izotropic has designed and is submitting to the FDA could potentially save America’s struggling health care systems billions of dollars – and would be extremely attractive for hospitals and health care managers.

A recent study found that the cost of follow-up imaging and diagnostic procedures after initial mammograms was more than $8 billion11 annually, just in the United States alone.

U.S. Government Funding and Patents

In addition to investor funds, approximately $20 million in U.S. government grants has been invested to develop this ground-breaking, potentially life-saving technology at the UC Davis Medical Center in Sacramento, California. Izotropic is primed to advance important initiatives, with news flow expected to be strong in the months ahead.

The fully-functioning prototype technology has been upgraded and reengineered by Izotropic’s engineers and technical team to deliver IzoView: a state-of-the-art breast imaging device for the future to be used on the masses. The experience and importance for patients, operators, insurance providers, and customers have been further studied by Izotropic to yield what the Company believes is a design and functionality that, once approved for sale, will drive demand, acceptance, and market uptake.

The researchers developing the IzoView platform have 10 unique U.S. patents and patent-pending applications, including for using breast CT to measure breast density, to perform robotic guided biopsies, to protect its unique radiation self-shielding design, and to incorporate a 3D-beam modulation filter that shapes IzoView’s x-ray beam to match the shape of the patient’s breast and further reducing the radiation dose.

The patent for biopsies is particularly noteworthy.  71 percent of the 1.6 million breast biopsies performed in the U.S. are found to be negative at the cost of $2.2 billion.14

Looking to the Future

Izotropic is setting up its long-term platform strategy to increase customer appeal with more add-ons.

After market entrance as a diagnostic device, the Company plans to offer solutions across the gamut of breast health care, including screening and diagnosis in radiology, treatment planning and monitoring in surgical oncology, and breast reconstruction and implant monitoring in plastic and reconstruction surgery.

A CEO and Scientific Advisory Team Like No Other

In addition, the management of Izotropic Corporation (OTCQB:IZOZF | CSE:IZOOTCQB:IZOZF | CSE:IZO) is fully committed to bringing this disruptive imaging technology to market.

Dr. John McGraw, MSc, Ph.D, CEO, Director

  • Senior VP of Business Development & Strategy, CML Healthcare (TSX: CLC) Canada’s largest provider of medical imaging services acquired by Lifelabs for C$1.2B.
  • VP Operations for Novadaq Technologies Inc. (NASDAQ: NCVQ), a medical device imaging company acquired by Styker Corporation for USD $701M.

Dr. John Boone, Principal Founder of Breast CT Technology & Director

  • Editor-In-Chief of Medical Physics, the official journal of the American Association of Physicists in Medicine (AAPM).
  • Commissioner of the International Commission of Radiation Units & Measurements (ICRU)
  • Co-author of “The Essential Physics of Medical Imaging,” the leading textbook for radiology residents

Dr. Younes Achkire, Ph.D., Chief Operating Officer

  • Founder, CTO/VP of Engineering & Operations at ZAP Surgical Systems, Inc.
  • VP of Engineering Equipment Technology & Operations at Solyndra
  • Engineering & Design Consultant, Varian Medical Systems

A Low-Priced Stock with Blockbuster Potential

As a publicly-traded company only founded in 2016, shares of Izotropic Corporation (OTCQB:IZOZF | CSE:IZOOTCQB:IZOZF | CSE:IZO) are currently selling for less than a dollar – but likely not for long.

The stock gained 112%12 from June 2022 to mid-January 2023, and is expected to garner a lot more attention throughout 2023.

Only about 51.813 million shares are outstanding.  That means the current market capitalization is tiny, especially given the “disruptive” nature of Izotropic’s technology and the fact that it’s the only publicly traded Company developing this kind of platform to address the growing problem of breast cancer.

Getting Ready to Launch

The Company is currently in the process of calibrating IzoView’s imaging processes – and is preparing for a clinical study to collect data that it will use for an FDA application for approval of an indication for use as a diagnostic device.

When FDA approval has been awarded, the Company will ramp up marketing of its revolutionary IzoView platform to the thousands of hospitals and clinics throughout the United States that perform breast imaging.

The Company is already participating in the FDA’s Center for Devices & Radiological Health Payor Communication Task Force program and can use historical trial data in discussions with insurance payers to demonstrate patient benefits for insurance coverage of the Company’s new IzoView platform.

Hundreds of Millions of Women Could Soon Demand This Technology

Women worldwide have already begun hearing about a brand-new, easy, and compression-free way to do breast imaging – lying comfortably for a few seconds on an imaging table rather than standing in front of an x-ray machine while their breasts are compressed between metal plates.

As word continues to get out, the demand for this disruptive new technology could be intense – and then all bets are off for shares in Izotropic Corporation (OTCQB:IZOZF | CSE:IZOOTCQB:IZOZF | CSE:IZO).

The time to investigate this Company is now, before it submits this major breakthrough in breast imaging technology to the FDA.

1  From $0.2590 at the close on June 28, 2022, to $0.54 per share at the close on Jan 13, 2023, per https://finance.yahoo.com/quote/IZOZF/history?p=IZOZF.  That was a gain of 112.3% in just over 6 months, per  https://percentagecalculator.net/
2  Closed at $14.42 per share on January 27, 2022, per https://finance.yahoo.com/quote/TMDX/history
3  Closed at $61.72 on December 30, 2022, per https://finance.yahoo.com/quote/TMDX/history
4  https://percentagecalculator.net/
5  https://izocorp.com/news-releases/izotropics-izoview-breast-ct-device-to-be-featured-on-advancements-tv-show-in-usa/
6  From $0.2590 at the close on June 28, 2022, to $0.54 per share at the close on Jan 13, 2023, per https://finance.yahoo.com/quote/IZOZF/history?p=IZOZF. That was a gain of 112.3% in just over 6 months, per  https://percentagecalculator.net/
7  https://www.cancer.org/content/dam/CRC/PDF/Public/8577.00.pdf
8  https://www.cancer.org/content/dam/CRC/PDF/Public/8577.00.pdf
9  https://www.marketsandmarkets.com/PressReleases/breast-imaging-technologies.asp
10  Corporate Presentation, September 2020, p. 10.
11 Slide 7, https://izocorp.com/site/assets/files/5623/final_jan_2023_izo_investor_presentation.pdf
12  From $0.2590 at the close on June 28, 2022 to $0.54 per share at the close on Jan 13, 2023, per https://finance.yahoo.com/quote/IZOZF/history?p=IZOZF.That was a gain of 112.3% in just over 6 months, per  https://percentagecalculator.net/
13  https://izocorp.com/site/assets/files/5623/final_jan_2023_izo_investor_presentation.pdf
14 Corporate Presentation, September 2020, p. 10.

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